Stem Cell Therapy for Neonatal Hypoxic-Ischemic Encephalopathy
نویسندگان
چکیده
منابع مشابه
Stem Cell Therapy in Hypoxic Ischemic Encephalopathy
Introduction there are one million deaths from asphyxia in newborn annually. Management of this newborn is only supportive. Autologuse stem cell therapy may reduce mortality and long term morbidity. Outcome of asphyxiated newborn is related to damage CNS cells. Stem cells prevent Apoptosis and induce repairmen of injured neurons. Methods in a review study all article related to three keyword...
متن کاملstem cell therapy in hypoxic ischemic encephalopathy
introduction there are one million deaths from asphyxia in newborn annually. management of this newborn is only supportive. autologuse stem cell therapy may reduce mortality and long term morbidity. outcome of asphyxiated newborn is related to damage cns cells. stem cells prevent apoptosis and induce repairmen of injured neurons. methods in a review study all article related to three keywords o...
متن کاملStem Cell Therapy for Neonatal Hypoxic-Ischemic Encephalopathy
Treatments for neonatal hypoxic-ischemic encephalopathy (HIE) have been limited. The aim of this paper is to offer translational research guidance on stem cell therapy for neonatal HIE by examining clinically relevant animal models, practical stem cell sources, safety and efficacy of endpoint assays, as well as a general understanding of modes of action of this cellular therapy. In order to do ...
متن کاملHypothermia: a neuroprotective therapy for neonatal hypoxic-ischemic encephalopathy.
t he incidence of hypoxic ischemic encephalopathy in the United States is 2.8/1000 live births of which 10–15% of the infants succumb and 25–30% suffer permanent neurologic damage: mental retardation, cerebral palsy and epilepsy. The incidence is tenfold higher in the developing world [1-3]. Experimental evidence has confirmed that HIE is an evolving process lasting hours to weeks. Understandin...
متن کاملSystemic hypothermia--a "cool" therapy for neonatal hypoxic-ischemic encephalopathy.
Hypoxic–ischemic encephalopathy is an important cause of death and disability in full-term infants. The incidence of moderate or severe hypoxic– ischemic encephalopathy has remained essentially unchanged over the past 20 years, at 1.5 to 2 per 1000 live births in the United States. Approximately 15 to 20 percent of these infants will die, and 20 to 25 percent of those who survive will be disabl...
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ژورنال
عنوان ژورنال: Frontiers in Neurology
سال: 2014
ISSN: 1664-2295
DOI: 10.3389/fneur.2014.00147